Vinorel 10 mg/ml Injection

Intravenous (Adult):

Cervical cancer:?30 mg/m² days 1 and 8 of a 21-day treatment cycle.

Breast cancer, Ovarian cancer:?25 mg/m² dose every 7 days.

Non-small cell lung cancer😕

• As single agent: 30 mg/m²?wkly as infusion over 20-30 minutes (after diluting in 125 ml normal saline or glucose 5%) or as slow bolus over 5-10 minutes (after diluting in 20-50 ml normal saline or glucose 5%). Delay subsequent doses if neutrophil count is <2000 cells/mm³?until recovery.
• As combination therapy with cisplatin: 25-30 mg/m²?every 7 days.

Oral?(Adult):

Non-small cell lung cancer:?60 mg/m²once wkly for 3 wk, may increase subsequently to 80 mg/m²?once wkly. If neutrophil count is < 500 cells/mm3?or between 500-1000 cells/mm3?on 2 separate occasions, keep dose at 60 mg/m²?for next 3 doses.