Darbesis – 25 mcg/0.42 ml SC Injection
2,569.92৳
Dosage : SC Injection
Strength : 25 mcg/0.42 ml
Generic : Darbepoetin Alfa
Pack Size : 1 Pack = NA
Manufacturer : Beacon Pharmaceuticals Ltd.
Usual Adult Dose for Anemia Associated with Chronic Renal Failure:
Chronic Kidney Disease (CKD) Patients Not on Dialysis:
- Initial dose: 0.45 mcg/kg IV or subcutaneously once every 4 weeks as appropriate
- Comments: Initiate treatment only when hemoglobin is less than 10 g/dL, rate of hemoglobin decline indicates likelihood of requiring RBC transfusion, and reducing risk of alloimmunization and/or other RBC transfusion-related risks is a goal.
CKD Patients on Dialysis:
- Initial dose: 0.45 mcg/kg IV or subcutaneously once a week or 0.75 mcg/kg once every 2 weeks as appropriate
- Comments: Initiate treatment when hemoglobin is less than 10 g/dL. IV route is recommended for patients on hemodialysis.
Usual Adult Dose for Anemia Associated with Chemotherapy:
- Initial dose: 2.25 mcg/kg subcutaneously once a week or 500 mcg subcutaneously once every 3 weeks
- Duration of therapy: Until completion of chemotherapy course
- Comments: Initiate treatment if hemoglobin is less than 10 g/dL and a minimum of 2 additional months of chemotherapy is planned. Use the lowest dose necessary to avoid RBC transfusions.
- Use: Treatment of anemia in patients with non-myeloid malignancies where anemia is due to the effect of concomitant myelosuppressive chemotherapy.
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