Cyphos 1 gm/vial IV Infusion

Intravenous (Adult)-

Malignancies:?

• Low dose regimen: 2-6 mg/kg wkly as a single dose;
• Moderate dose regimen: 10-15 mg/kg wkly as a single dose;
• High dose regimen: 20-40 mg/kg as a single dose every 10-20 days.

Alternatively,

• 80-300 mg/m²?daily as a single dose, or
• 300-600 mg/m²?wkly as a single dose, or
• 600-1,500 mg/m²?as a single dose or
• Short infusion at 10- to 20-day intervals.

Oral?(Child)-

Nephrotic syndrome:?

• 2 mg/kg daily for 8-12 wk.
• Max cumulative dose: 168 mg/kg.
• Max duration: 90 days.

Oral?(Adult)-

Malignancies:?

• Low dose regimen: 2-6 mg/kg wkly in divided dose.
• Alternatively, 100-300 mg daily in divided doses, or
• 50-250 mg/m²?daily or 80-300 mg/m²?daily in divided doses.