Colistimethate (CMS) – 4.5 MIU IM/IV Injection

1,990.78৳ 

Dosage : IM/IV Injection
Strength : 4.5 MIU
Generic : Colistimethate Sodium
Pack Size : 1 Pack = NA
Manufacturer : Xellia Pharmaceuticals, Denmark

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  • Colistimethate (CMS) - 4.5 MIU IM/IV Injection

    1,990.78৳ 

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      Colistimethate (CMS) - 4.5 MIU IM/IV Injection

      1,990.78৳ 

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      Maintenance dose: 9 MIU/day in 2-3 divided doses. In patients who are critically ill, a loading dose of 9 MIU should be administered.

      Renal impairment patients: Dose adjustments in renal impairment patients are necessary. Dose reductions are recommended for patients with creatinine clearance < 50 ml/min. Twice daily dosing is recommended.

      • Creatinine clearance <50-30 ml/min: daily dose 5.5-7.5 MIU
      • Creatinine clearance <30-10 ml/min: daily dose 4.5-5.5 MIU
      • Creatinine clearance <10 ml/min: daily dose 3.5 MIU

      Haemodialysis (HD) patients:

      • No-HD days: 2.25 MIU/day (2.2-2.3 MIU/day).
      • HD days: 3 MIU/day (Should be given after the HD session) Twice daily dosing is recommended.

      Pediatric population: The dose should be based on lean body weight.

      • Children ?40 kg: 75,000-150,000 IU/kg/day divided into 3 doses.
      • Children >40 kg: >150,000 IU/kg/day has been reported in children with cystic fibrosis.

      Hepatic impairment patients: There are no data in patients with hepatic impairment. Caution is advised when administering colistimethate sodium in these patients.

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