• Adults and adolescents 12 years and older: 2 puffs of 25 ?g Salmeterol and 50 ?g Fluticasone Propionate twice daily or 2 puffs of 25 ?g Salmeterol and 125 ?g Fluticasone Propionate twice daily or 2 puffs of 25 ?g Salmeterol and 250 ?g Fluticasone Propionate twice daily.
• Children (4-12 years): 2 puffs of 25 ?g salmeterol and 50 ?g Fluticasone Propionate twice daily.

Inhalation Powder in Capsule (For Asthma):

• Adult and Adolescent (12 Years and Older): Salmeterol 50 ?g & Fluticasone 100 ?g or?Salmeterol?50 ?g & Fluticasone 250 ?g twice daily (morning and evening, approximately 12 hours apart).?
• The recommended starting dosages for?Salmeterol?50 ?g & Fluticasone?100 ?g &?Salmeterol?50 ?g & Fluticasone 250 ?g for patients aged 12 years and older are based upon patients asthma severity.?
• The maximum recommended dosage is?Salmeterol?50 ?g & Fluticasone 500 ?g twice daily.
• Pediatric Patients (4 to 11 Years): For patients with asthma who are not controlled on an inhaled corticosteroid, the dosage is Salmeterol?50 ?g & Fluticasone?100 ?g twice daily (morning and evening, approximately 12 hours apart).

Inhalation Powder in Capsule (For COPD): Salmeterol 50 ?g & Fluticasone 250 ?g twice daily (morning and evening, approximately 12 hours apart). Rinsing the mouth after each inhalation is advised.

Inhalation Powder in Maxhaler (For Asthma): This is a moulded plastic device containing a foil strip with 60 regularly placed blisters containing pre-dispensed inhalation powder. Patients should be made aware that Maxhaler must be used daily for optimum benefit, even when asymptomatic.

Adults and Adolescents (12 years and older)-

• 50/100 Maxhaler: One Inhalation twice daily
• 50/250 Maxhaler: One Inhalation twice daily
• 50/500 Maxhaler: One Inhalation twice daily

Children (4 years and older)-

• 50/100 Maxhaler: One Inhalation twice daily. The maximum licensed dose of fluticasone propionate delivered by this Maxhaler in children is 100 ug twice daily. There are no data available for use of this Maxhaler in children aged under 4 years.

Inhalation Powder in Maxhaler (For COPD):

• Maxhaler: One Inhalation twice daily
• Special patient groups: There is no need to adjust the dose in elderly patients or in those with renal impairment. There are no data available for use of this in patients with hepatic impairment.
• Using the Maxhaler: This is a patient friendly, ready to use and easy to grip device. Use as per instructions for use.