• Adult:?500 mg daily.
• Child:?<10 yr?Half of adult routine dosage.

Intraperitoneal:
Supplement in systemic therapy for treatment of susceptible infections-

• Adult:?500 mg daily.
• Child:?<10 yr?Half of adult routine dosage.

Intrapleural:
Supplement in systemic therapy for treatment of susceptible infections-

• Adult:?500 mg daily.
• Child:?<10 yr?Half of adult routine dosage

Intravenous:
Meningitis-

• Adult:?2 gm 6 hrly.
• Child:?150 mg/kg daily in divided doses.

Intrapartum prophylaxis against group B Streptoccocal infection in neonates-

• Adult:?Initially, 2 gm via IV inj followed by 1 gm 4 hrly until delivery.

Oral:
Biliary tract infections, Bronchitis, Endocarditis, Gastroenteritis, Listeriosis, Otitis media, Perinatal streptococcal infections, Peritonitis-

• Adult:?0.25-1 gm 6 hrly.
• Child:?<10 yr?Half of adult routine dosage.

Typhoid and paratyphoid fever-

• Adult:?1-2 gm 6 hrly for 2 wk in acute infections, and 4-12 wk in carriers.

Uncomplicated gonorrhoea-

• Adult:?2 gm with 1 gm of probenecid as single dose, recommended to be repeated in female patients.

Urinary tract infections-

• Adult:?500 mg 8 hrly.

Parenteral:
Susceptible infections-

• Adult:?500 mg 6 hrly, via IM or slow IV inj over 3-5 min or by infusion.
• Child:?<10 yr?Half of adult routine dosage.

Septicaemia-

• Adult:?150-200 mg/kg daily. Initiate with IV admin for at least 3 days, then continue with IM inj 3-4 hrly. Continue treatment for at least 48-72 hr after the patient has become asymptomatic or when there is evidence of bacterial eradication. Recommended treatment duration for infections caused by group-A ?-haemolytic streptococci: At least 10-days, to prevent occurrence of acute rheumatic fever or acute glomerulonephritis.
• Child:?Same as adult dose.